Huijin (Ginny) An, a graduate student in interdisciplinary materials science at 91�Թ���, has been awarded the Parkhutik Prize for the most outstanding poster at the recent Porous Semiconductors Science and Technology (PSST) conference in Naples, Italy.

The Parkhutik Prize recognizes outstanding contributions in the field of porous silicon and related semiconductor technologies. It honors the legacy of pioneering physicist Vitali Parkhutik, who dedicated more than three decades to research on porous silicon, anodization processes, and the development of advanced characterization techniques

She was recognized for her work “Control of Fluid Flow in Paper-Based Porous Silicon Biosensor for Enhanced Sensor Performance.”��Her research shows how controlling fluid flow in paper-based porous silicon sensors can significantly enhance detection efficiency. By optimizing microchannel design. Her approach achieved more than a twofold increase in signal for protein detection within a 20-minute testing window.

This recognition highlights An’s contribution to advancing rapid, sensitive diagnostic technologies.

An is a member of the ��led by , Cornelius 91�Թ��� Professor of Engineering and director of the ��(�ձ�������).

How can tiny structures in your favorite berry turn sunlight into electricity? On Monday, May 4th, VINSE welcomed students from White County High School to the Blackberry Solar Cell Lab for an interactive dive into solar energy and nanoscience. Students crafted working solar cells using blackberry juice and measured the power their homemade devices could produce.

The visit also gave students a chance to explore the materials at a microscopic level using one of VINSE’s scanning electron microscopes. With magnification up to 500,000 times, students were able to see nanoscale features tens of thousands of times smaller than a human hair, gaining insight into how these tiny details affect a solar cell’s ability to capture sunlight.

A big thank-you to VINSE NanoGuides Kauryn Datcher, Emily Rouse, Gillian Vansciver, and Madison Walker for making this hands-on learning experience so engaging.

Schools interested in this program can reach out to vinse@vanderbilt.edu�� to learn more.

Congratulations to Ikjun Hong and the team members in Justus Ndukaife lab! Ikjun’s paper, “Rapid trapping and label-free optical characterization of single nanoscale extracellular vesicles and nanoparticles in solution,” has been featured as a VINSE Spotlight publication and published in Light: Science & Applications. This work was carried out with collaboration with 91�Թ��� Medical Center (VUMC).

Despite the advances in single particle trapping and characterization, we note that a scalable platform that offers simultaneous high-efficiency trapping, label-free imaging, and molecular composition analysis of individual nanoparticles remains elusive. Such a tool would significantly advance single-particle analysis by enabling rapid, detailed characterization of both size and chemical composition at the nanoscale, with profound implications across a range of fields, from nanomedicine to environmental science. Although laser trapping Raman spectroscopy can trap micro-scale particles and collect Raman scattering signals, the process often requires at least several minutes to load, optically trap, and perform Raman analysis, which dramatically limits analysis throughput. To address this critical gap, we introduce an original interferometric electrohydrodynamic tweezers (IET). IET uses electrohydrodynamic flows to rapidly trap thousands of nanoscale objects, such as EVs and nanoparticles, in parallel—within seconds. Our platform integrates label-free interferometric imaging and molecular composition analysis using Raman spectroscopy, enabling precise, real-time characterization at the single particle level without the need for fluorescent labels or surface immobilization. Importantly, IET allows for the comprehensive analysis of nanoscale particles (including size, shape, and chemical composition) in their native state, avoiding artifacts introduced by traditional staining or fixation techniques.

Read article here in the .

Authors: Ikjun Hong, Chuchuan Hong, Theodore Anyika, Guodong Zhu, Maxwell Ugwu, James N Higginbotham, Jeffrey L Franklin, Robert Coffey, Justus C Ndukaife

Abstract: Achieving high-efficiency, comprehensive analysis of single nanoparticles to determine their size, shape, and composition is essential for understanding particle heterogeneity with applications ranging from drug delivery to environmental monitoring. Existing techniques are hindered by low throughput, lengthy trapping times, irreversible particle adsorption, or limited characterization capabilities. Here, we introduce Interferometric Electrohydrodynamic Tweezers (IET), an integrated platform that combines rapid molecular trapping, interferometric scattering imaging, and Raman scattering to rapidly trap and characterize single nanoparticles within seconds in one integrated platform. The IET platform enables to perform both trapping and Raman analysis within seconds in contrast with laser trapping Raman spectroscopy that often require several minutes per measurement. Furthermore, the IET platform can also operate under low particle concentration media, where particle loading is slow for conventional laser trapping Raman spectroscopy approach. We demonstrate the platform’s capabilities by trapping and characterizing the size and chemical composition of colloidal polymer beads and nanoscale extracellular vesicles (EVs), while trapped in solution. Our IET represents a powerful optofluidics platform for comprehensive characterization of nanoscale objects, opening new avenues in nanomedicine, environmental monitoring, and beyond.

Congratulations to Mark Mc Veigh and the Bellan group! Mark’s paper, “Understanding the Compatibility of Fluoride-Based Radiopharmaceutical Reaction Solutions and PDMS” has been featured as a VINSE Spotlight publication and published in ACS Applied Materials and Interfaces.

Nuclear medicine has become an integral tool for physicians to diagnose and treat cancer and various other diseases. This growth has been enabled by the ongoing development of thousands of targeted radiopharmaceuticals (RPs) designed to track specific biological processes. Currently, production methods rely on economies of scale to reduce costs, meaning lesser used but more targeted RPs are prohibitively expensive for the patient. Microfluidics has been identified as a key technology that can reduce this cost barrier by enabling decentralized dose-on-demand RP production. Using a microfluidic synthesis platform, PET scan facilities and radiopharmacies can produce single doses of RPs and directly distribute them to patients. This eliminates the waste associated with large batches and reduces cost for patients. As these systems transition from research to commercialization, understanding material compatibility has become a critical concern. In particular, polydimethylsiloxane (PDMS), a material widely used to fabricate microfluidic devices, has been the subject of significant debate due to conflicting reports on its interaction with ¹⁸F, with some studies reporting severe activity losses and others reporting minimal effects.

In this work, scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDS), profilometry, and gas chromatography mass spectrometry (GC-MS) were used to directly probe the interaction between fluoride-based reaction solutions and PDMS. SEM-EDS revealed that fluoride does not significantly diffuse into PDMS and can largely be removed by washing with appropriate solvents. However, images showed significant damage to the surface if the reaction solution was completely evaporated on the surface (a necessary step in many radiofluorination processes). The damage was confirmed and quantified with profilometry which provided further insight that substantial surface etching occurred only after complete solvent evaporation (when crystallized salts contact the PDMS surface). GC-MS identified several volatile compounds that are created during this interaction including the F-containing species trimethylfluorosilane. Together, these results reconcile previously conflicting reports by showing that PDMS remains largely stable during exposure to liquid-phase reaction solutions but degrades to form F-containing volatile species once the solution is fully evaporated, resulting in significant activity loss.

Read full article in

Authors: Mark Mc Veigh, Charles Frech, Mai Lin, Robert Ta, H. Charles Manning, and Leon M. Bellan

Abstract: Microfluidic devices offer unique and exciting benefits when applied to radiopharmaceutical manufacturing, and these platforms are now starting to be integrated into commercial products. The field has strayed away from the use of polydimethylsiloxane (PDMS), the most common microfluidic device material, due to its suspected incompatibility with 18F, the most commonly used radionuclide. However, existing literature provides conflicting conclusions as to the existence and extent of this incompatibility. In this study, we use several analytical instruments to uncover the underlying interaction between fluoride and PDMS. SEM imaging and profilometry confirm the reactive relationship between the two materials and suggest that this interaction only occurs when the reaction solution is fully evaporated and crystallized salts are in contact with PDMS. Furthermore, GC-MS identifies fluoride-containing volatile species that can account for loss of fluoride in previous studies and additionally reveals an incompatibility between PDMS and K2CO3 (a commonly used component of radiofluorination reaction solutions). These results confirm the need for microfluidic radiofluorination devices to avoid the use of PDMS in most contexts but may allow for inexpensive design and testing of liquid state operations (such as concentration, purification, and mixing) using the material.

Instructor: Hanna Terletska
Director, QRISE Center at MTSU

Curious about how quantum computers work and how you can start programming one? This full-day workshop takes you on a journey from the fundamental principles of quantum science to writing and running real quantum algorithms on IBM’s quantum hardware.

Attendees are welcome to join the morning session, the afternoon session, or stay for the full day experience.

Morning session – Foundations & Refresher

This day begins with an overview of the core concepts underpinning����quantum computing.

• Explore the quantum materials and physical systems used to build real quantum processors
• Learn how quantum information is stored and manipulated using qubits
• Get hands-on with basic quantum gates and circults

Afternoon session – Deeper Dive into Quantum Computing with Qiskit

In the second part of the workshop, we will shift into a deeper, more technical exploration of quantum algorithms.

• Deeper dive into quantum algorithms
• Write, simulate and execute multi-step quantum algorithms using Qiskit
• Run your programs on actual IBM quantum computers
• Guided coding exercises will walk participants through each algorithm step-by-step, with time for experimentation and discussion

No prior quantum computing experience is required, ��just your curiosity and a willingness to dive in. Designed for students across STEM disciplines.

VINSE recently hosted its 12th annual Student-Selected Keynote, featuring Prof. Guihua Yu (University of Texas at Austin), a leading researcher in materials science and energy technologies. Selected by VINSE graduate students, this keynote reflects the interests and direction of emerging researchers and continues to be a distinctive part of the institute’s programming.

Prof. Yu’s talk focused on the design of engineered soft materials, particularly hydrogels, and their applications in energy storage, water purification, and broader sustainability challenges. His visit also included a full day of engagement with the VINSE community, including small-group discussions with students and faculty.

VINSE thanks Prof. Yu for his time, insight, and willingness to engage across the community.

This event was organized by the 2026 VINSE Keynote Address Committee, chaired by Rahul Shah, with Owen Meilander, Grace Adams, Daniel P. Woods, Jeb Buchner, and Zacchaeus Wallace.

Congratulations to Owen Meilander and his collaborators! Owen’s paper, “Micro-transfer printing of GaN HEMTs on engineered substrates for use in harsh environments,” has been featured as a VINSE Spotlight publication and published in APL Electronic Devices. This work was carried out in the Mona Ebrish Lab, with contributions from co-author and former VINSE REU summer fellow Lisa Sebastian.

Gallium nitride (GaN) high electron mobility transistors (HEMTs) promise high efficiency and performance for high-power and high-frequency applications due to its wide bandgap and high electron mobility. However, the lack of native complementary logic in GaN necessitates its integration with standard CMOS controllers. While discrete packaging on a PCB level provides a temporary solution, it compromises device efficiency and size, driving the need for a scalable, direct on-chip heterogeneous integration method.

In this work, we demonstrate a scalable heterogeneous integration approach utilizing micro-transfer printing to bond GaN HEMTs released from 8-inch, CMOS-compatible Qromis Substrate Technology wafers to arbitrary target substrates. By selectively etching a silicon seed layer and employing a PDMS stamp for deterministic placement, this technique achieved a transfer success rate exceeding 95% with minimal device degradation after bonding. Our results reveal that managing residual biaxial stress is critical. By controlling the thickness of the buffer layers beneath the active device, the observed strain relaxation resulting in a more than 12 μm bend across the transferred layer was reduced to less than 1 μm. Finally, the transferred devices proved robust against extreme environmental conditions. They survived both the vacuum of space and temperature fluctuations from 8 to 473 K without delamination or loss of electrical performance. This industry-compatible methodology offers a viable pathway for integrating GaN power electronics into next-generation systems, paving the way for more efficient and compact technology operating in the most demanding environments.

Read article here in the

Authors: O.R. Meilander, L. Sebastian, E. Riglioni, H.E. Dishman, and M.A. Ebrish

Abstract: Heterogeneous integration of gallium nitride (GaN) devices is essential to overcome the intrinsic material limitations in advanced electronics. For the successful incorporation of an integration technique into industry, a highly scalable process must be developed. In this work, the heterogeneous integration of GaN high electron mobility transistors (HEMTs) through a micro-transfer printing process is demonstrated. This scalable technique involving HEMTs fabricated on commercially available and CMOS-compatible 8′′ GaN on engineered substrate resulted in a high (>95%) transfer success rate and limited device degradation. Transfer was demonstrated to multiple adhesion layers, including copper tape and KMSF 1000 photo-dielectric. The limited degradation that was observed is attributed to a change in stress after transfer, as measured
by the Raman spectroscopy. Finally, the viability of the adhesion layer for use in harsh environments was tested. No delamination, significant outgassing, or degradation of electrical properties were observed when the sample was placed under a vacuum or when the temperature was varied between 8 and 473 K. This makes the process an ideal choice for systems intended for space applications.

Tao Hong, Interdisciplinary Materials Science
*under the supervision of Jason Valentine

“Metasurface-on-chip Flow Cytometer for Fluorescence Quantification”

5.13.26 | 9:30 am | 306 FGH |

Fluorescence flow cytometry (FFC) is a fundamental technique to cellular and molecular analysis, yet conventional instruments rely on bulky free-space optics and expert-driven workflows for channel calibration and compensation. We introduce a compact and calibration-free, metasurface-on-chip FFC that replaces filter assemblies or spectrometers with inverse-designed metasurface array that encodes fluorescence spectra into spatially multiplexed intensity barcodes. We demonstrate statistical profiling of immunolabeled cell populations based on regressed per-fluorophore quantity and extend the approach to multi-cytokine quantification by using a commercial Cytometric Bead Assay (CBA), without the need of channel calibration. By encoding spectral information by a compact on-chip optical metasurface front end and decoding it with end-to-end spectral regression, this metasurface architecture enables quantitative, multi-fluorophore FFC in a compact format, opening a promising path toward portable, point-of-care cellular and molecular analysis.

We started this last year. This summer, we’re building on that momentum.

NanoExchange is back for Summer 2026, continuing to rethink the traditional seminar format. Designed by students, this series transforms the typical research talk into an open, interactive forum for sharing ideas, asking questions, and building community.

What is NanoExchange?
NanoExchange focuses on conversation over presentation. Each session features short, informal exchanges where presenters share works-in-progress, early ideas, or research pivots, followed by open discussion. It’s less about polished results and more about exploration, curiosity, and collaborative thinking.

Why NanoExchange?
Because science moves forward through dialogue. NanoExchange creates a relaxed, supportive space for graduate students and postdocs to connect across disciplines, get feedback, and spark new collaborations.

Summer 2026 Schedule
Thursdays | 10:00 – 11:30
Coffee & Snacks: 10:00 – 10:30 AM | NanoExchange Sessions: 10:30 – 11:30 AM

Location: 202 Light Hall

The Summer 2026 series will feature presenters from across engineering, materials science, chemistry, and biomedical research.

May 28 – Week 1��

• Jacob Clerc – On-chip THz Spectroscopy of Quantum Materials��
• Sarah Lyons – Engineering an siRNA-Peptide Conjugate for Enhanced Biodistribution and Neuron Targeting

June 4 – Week 2

• Ben Schmidt – Tools and Capabilities in VINSE Core Facilities
• Emmanuel Dabuo – Developing Scattering-Scanning Near Optical Microscopy (s-SNOM) and Nano-FTIR for Nanoscale Defect Characterization in Wide-Bandgap Semiconductors

June 11 – Week 3

• Emanuela (Emi) Riglioni – Mode Hybridization in Photonic Crystal Structures
• Emily Byrum – Development of Novel Electric Arc Furnace Slag Geopolymer Cements for 3D Printing��

July 9 – Week 4

• Grant Mayberry – Dangling-bond Conductive Nanowires in Irradiated Wide-bandgap Semiconductor��
• Madison Walker – Noninvasive Screening of Eosinophilic Esophagitis using Saliva and Raman Spectroscopy��

July 16 – Week 5

• Yinan Yang – Decoding Order and Disorder in High-Entropy MAX Phases
• Madisen Domayer – Bioadhesive Hybrid Hydrogels for Osteoarthritis

July 23 – Week 6

• Vikash Khokhar – Universal��Effect of��Ammonia��Pressure on��Synthesis of��Colloidal��Metal��Nitrides in��Molten��Salts
• Mia Woodruff – Albumin-Hitchhiking Nanobody-Antigen Fusions for Inducing Antigen-Specific Immune Tolerance��

This summer’s NanoExchange is chaired by IMS Graduate Students Jack Loken and Jojo Pearson.

Come for the coffee, stay for the conversation. Let’s keep rethinking how we share science – together.

Join us for the first session of the NanoExchange Summer Series, featuring two graduate researchers sharing their work and opening the floor for discussion. This inaugural session sets the tone for a summer of informal, interactive scientific exchange.

This summer’s NanoExchange is chaired by IMS Graduate Students Jack Loken and Jojo Pearson.

Date: Thursday, May 28, 2026
Coffee and Snacks: 10:00 to 10:30 AM
NanoExchange Sessions: 10:30 to 11:30 AM
Location: 202 Light Hall

Jacob Clerc | On-chip THz Spectroscopy of Quantum Materials
Quantum materials exhibit��interesting emergent behavior on energy scales corresponding to the THz range of the electromagnetic spectrum, including superconductivity and magnetism. However, because of the nanoscale size of these systems, many of these phenomena cannot be easily studied using traditional THz spectroscopy techniques. To overcome this barrier, we are designing and fabricating THz circuits which serve as on-chip spectrometers. These devices bypass the diffraction limit by confining THz generation, emission, and referencing all to a single substrate. We can��leverage��these circuits to investigate the behavior of��vdW��materials and engineered heterostructures, which may��exhibit��complex quantum phases. To this end, we plan to harness this technique to investigate the superconducting properties of��vdW��materials such as 4Hb-TaS2, thereby advancing our understanding of unconventional superconductivity and laying foundations for new��vdW-based quantum circuitry.��

Sarah Lyons | Engineering an siRNA-Peptide Conjugate for Enhanced Biodistribution and Neuron Targeting in the Central Nervous System��
Sarah Lyons is a third year Ph.D. student studying Chemical and Biomolecular Engineering in the Lippmann Lab. Her research focuses on engineering lipid- and peptide- siRNA conjugates to enhance delivery across the central nervous system, with an emphasis on improving biodistribution and gene silencing in neurons. Prior to 91�Թ���, she earned her B.S. in Chemical Engineering from the University of Rhode Island, where she conducted research spanning nanomaterials, drug delivery, and machine learning for immune cell phenotyping.����