
Join us for Week 5 of the NanoExchange Summer Series. Each session brings together graduate researchers to share work-in-progress, explore new ideas, and engage in open discussion across disciplines.
This summer’s NanoExchange is chaired by IMS Graduate Students Jack Loken and Jojo Pearson.
Date: Thursday, July 16, 2026
Coffee and Snacks: 10:00 to 10:30 AM
NanoExchange Sessions: 10:30 to 11:30 AM
Location: 202 Light Hall
Yinan Yang |Decoding Order and Disorder in High-Entropy MAX Phases
We present a systematic investigation into the structural ordering principles of high-entropy MAX phases through combined density functional theory (DFT) and experimental characterization. Despite their name suggesting disorder, our findings reveal these materials are not completely random. Our comprehensive study across ~50 different compositions (spanning 2-9 metal elements)ÌýdemonstratesÌýthat enthalpy initially keeps metals in preferred positions until entropy becomes strong enough to overcome this ordering. The layered architecture of MAX phases—where metal atoms are sandwiched between carbon and aluminum layers—provides an exceptional platform for studying fundamental order-disorder transitions. We further quantified the surface properties and electronic behavior in the material’sÌýMXeneÌýform and showed their dependence onÌýordering,Ìýopening possibilities for customized materials. Our work addresses longstanding questionsÌýregardingÌýthe nature of high-entropy materials byÌýestablishingÌýa quantitative framework for predicting element distribution, enabling rational design of layered materials with tailored functionalities for catalysis, energy storage, and electronic applications.Ìý
Madisen Domayer| Bioadhesive, Hybrid Hyaluronic Acid and Nanoparticle HydrogelsÌý
Osteoarthritis is a chronic condition that leads to the degradation of cartilage, causing joint pain and disability. Current treatment options include corticosteroid and hyaluronic acid (HA) injections, but these treatments only provide temporary relief and do notÌýslowÌýthe progression of the disease. As a result, patients are often ultimately relegated to total joint replacement. HA consistently reduces joint pain associated with OA, but the half-life of HA isÌýrelatively short. WeÌýseekÌýtoÌýmodifyÌýHA to createÌýbioadhesive, shear-thinning hydrogels that are composites of HA and nanoparticles. This designÌýseeksÌýto provide prolonged patient relief and an opportunity to combine the benefits of HA with sustained local drug release from the nanoparticleÌýcomponentÌýof the hydrogel. Furthermore, the NPs will be formed from polysulfides, an ROS-responsive class of polymers that have inherent antioxidant and therapeutic functions in the context of OA.Ìý
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